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課程名稱 |
臨床影像學二
Fundamentals of Medical Imaging(Ⅱ) |
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開課學期 |
109-2 |
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授課對象 |
醫學院 物治系六年制 |
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授課教師 |
湯佩芳 |
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課號 |
PT4038 |
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課程識別碼 |
408 43340 |
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班次 |
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學分 |
1.0 |
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全/半年 |
半年 |
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必/選修 |
必帶 |
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上課時間 |
星期三9(16:30~17:20) |
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上課地點 |
實習教室 |
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備註 |
與邱銘章、鄭建興、彭信逢、周弘傑、陳雅芳、賴達明、林靜嫻、湯頌君、吳文超合授
限本系所學生(含輔系、雙修生) 且 限學士班四年級以上
總人數上限：45人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1092PT4038_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
本課程為物理治療學系六年學制學生之必修課程，課程內容為成人與小兒常見神經內外科疾病之神經、血管臨床影像判讀，以養成物理治療核心專業能力。內容主要涵蓋﹕(一)神經發展與神經解剖學概觀;(二)電腦斷層(含電腦斷層灌流)造影、磁振造影、血管攝影、正子攝影、與神經超音波等影像成像原理之介紹;(三)正常與異常影像判讀原則;(四)主要成人與小兒神經內外科疾病(含腦中風、頭部外傷、水腦、腦腫瘤、巴金森氏症、失智症、脊髓損傷、脊髓腫瘤與病變、腦性麻痺、遺傳性腦疾病、腦先天畸形等)之神經、血管臨床影像判讀。本課程採多元學習方式進行，除授課教師講授相關知識之外，亦包含問題導向學習(PBL)、課堂討論與報告等學習活動，以培養學生專業能力、批判思考、終身學習、和跨領域溝通以及團隊合作能力。 |
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課程目標 |
修習學生在結束本課程後，應能：
1. 瞭解電腦斷層、磁振造影、血管攝影、正子攝影、與神經超音波等之影像原理；
2. 瞭解如何判讀正常之電腦斷層腦與磁振造影腦部與脊髓影像；
3. 瞭解如何判讀血管攝影與神經超音波影像；
4. 瞭解如何判讀主要成人即小兒神經內外科疾病之神經、血管影像；
5. 瞭解神經、血管影像判讀結果與臨床表徵間的關係；
6. 學習應用神經、血管影像資訊於成人神經物理治療及小兒神經物理治療主要臨床疾病類別之臨床決策。 |
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課程要求 |
先修科目: 機能解剖學 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
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指定閱讀 |
待補 |
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參考書目 |
I. Neuroanatomy textbooks
A. Haines DE. Neuroanatomy: An Atlas of Structures, Sections, and
Systems. 9th Ed. Philadelphia: Wolters Kluwer. 2015.
B. Kiernan JA, Rajakumar N. Barr’s The Human Nervous System: An
anatomical Viewpoint. 10th Ed. Philadelphia: Wolters Kluwer Lippincott
Williams & Wilkins, 2014.
C. Mai JK and Paxinos G. The human nervous system [electronic
resource]. 3rd Ed. Burlington: Elsevier Science, 2011
D. Mai JK, Paxinos G, Voss T. Atlas of the human brain. 3rd Ed. New
York: Academic Press. 2008.
E. Vanderah, TW. Nolte’s the Human Brain: An Introduction to Its
Functional Anatomy [electronic resource]. 7th ed. Philadelphia, PA:
Elsevier. 2016.
II. Neuroscience textbooks
A. Bear M, Connors B, Paradiso M. Neuroscience: Exploring the brain, 3
ed. Baltimore: Lippincott Williams & Wilkins. 2016.
B. Purves D, Augustine GJ, Fitzpatrick D, Hall WC, LaMantia A-W, White
LE. Editors. Neuroscience. 5th Ed. Sunderland, MA, USA: Sinaur Associates,
Inc. 2012.
C. Lundy-Ekman L. Neuroscience Fundamentals for Rehabilitation. 4rd ed.
St. Louis: Saunders Elsevier; 2013
III. Neuroimaging textbooks
A. Cho ZH (Editor). 7.0 Tesla MRI Brain Atlas (2nd Ed.) [electronic
resource]. Berlin, Heidelberg: Springer. 2015.
B. Gillard JH, Waldman AD, and Barker PB. Clinical MR Neuroimaging:
Physiological and Functional Techniques (2nd ed). New York: Cambridge
University Press. 2010.
C. Naidich TP. Duvernoy's Atlas of the Human Brain Stem and Cerebellum
[electronic resource]: High-field MRI: Surface Anatomy, Internal Structure,
Vascularization and 3D Sectional Anatomy. Vienna: Springer Vienna. 2009.
D. Sanelli PC et al. Neuroimaging: the Essentials. Philadelphia:
Wolters Kluwer. 2016.
E. Scarobino T, Pollice S, Popolizio T (Editors). High Field Brain MRI:
Use in Clinical Practice (2nd Ed.) [electronic resource]. Cham: Springer
International Publishing. 2017.
F. Scott W. Atlas (Editor). Magnetic Resonance Imaging of the Brain and
Spine [electronic resource]. 5th ed. Philadelphia: Lippincott Williams &
Wilkins, 2017.
G. Scott W. Atlas (Editor) MRI of the brain and spine [electronic
resource]. Philadelphia: Lippincott Williams & Wilkins. 2008.
H. Talairach, J. Co-planar Stereotaxic Atlas of the Human Brain : 3-
dimensional Proportional System: An Approach to Medical Cerebral Imaging.
NY: Thieme Medical Publishers.
I. Westbrook C, Roth CK, TalbotJ. MRI in Practice (4th ed). Chichester,
West Sussex ; Malden, MA : Wiley-Blackwell. 2011.
J. Westbrook C. MRI at a Glance (2nd ed). Chichester, U.K. ; Malden, MA
: Wiley-Blackwell. 2010.
K. 陳煥武編譯(Catherine Westbrook原著)。圖解核磁共振造影學。台北市:合記。
2006。
IV. Other readings: to be determined by instructors
A. Basic principles of imaging
1. Goldman LW. Principles of CT and CT technology. J Nucl Med Technol
2007;35:115-128; quiz 129-130.
2. Currie S, Hoggard N, Craven IJ, Hadjivassiliou M, Wilkinson ID.
Understanding MRI: basic MR physics for physicians. Postgrad Med J
2013;89:209-223.
3. Townsend DW. Physical principles and technology of clinical PET
imaging. Ann Acad Med Singapore 2004;33:133-145.
B. Aging brain
1. Jagust W, D’Esposito M. Imaging the Aging Brain [electronic
resource]. Oxford Scholarship Online. 2009.
C. Stroke
1. Bivard A, Spratt N, Miteff F, Levi C, Parsons MW. Tissue Is More
Important than Time in Stroke Patients Being Assessed for Thrombolysis.
Frontiers in neurology 2018;9:41.
2. Campbell BC, Parsons MW. Imaging selection for acute stroke
intervention. Int J Stroke 2018;13:554-567.
3. Tsivgoulis G, Katsanos AH, Schellinger PD, et al. Advanced
Neuroimaging in Stroke Patient Selection for Mechanical Thrombectomy. Stroke
2018;49:3067-3070.
4. Vilela P, Rowley HA. Brain ischemia: CT and MRI techniques in acute
ischemic stroke. Eur J Radiol 2017;96:162-172.
V. Other electronic resources
A. de Asis Bravo-Rodriguez F, Diaz-Aguilera R. Hygino Cruz Jr. LC.
(Editors) Learning Neuroimaging [electronic resource]: 100 essential cases.
Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg. 2012.
B. Espinosa PS, Smith CD. Neurology Self-Assessment: Focus on
Neuroimaging [electronic resource]. Philadelphia: Lippincott Williams &
Wilkins. 2009. (叢書名Neurology self-assessment)
C. Barkovich AJ, Raybaud C. Pediatric Neuroimaging [electronic
resource]. Philadelphia: Wolters Kluwer Health/Lippincott Williams &
Wilkins. 2012.
D. Barkhof F. et al. Neuroimaging in Dementia [electronic resource].
Berlin, Heidelberg : Springer-Verlag Berlin Heidelberg. 2011.
E. https://3d4medical.com/apps/radiology-head |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
上課參與、討論、及報告 |
20% |
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2. |
期中考 |
40% |
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3. |
期末考 |
40% |
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週次 |
日期 |
單元主題 |
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第1週 |
2/24 |
Course overview
Review of CNS and its development |
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第2週 |
3/3 |
Review of brain anatomy using brain slices and on-line resources |
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第3週 |
3/10 |
Introduction to medical imaging: CT (non-contrast, contrast, perfusion, angiography), MRI (basic structure, diffusion, susceptibility, angiography, perfusion, and spectroscopy), and PET (PET CT) |
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第4週 |
3/17 |
Use of neuroimaging in neurorehabilitation: readings & homework |
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第5週 |
3/24 |
PBL: Stroke neuroimaging (4 groups) 10-12 mins/group
(Brain images and clinical correlates of patients with stroke involving the ACA, MCA, PCA, and VA-BA arterial territories) |
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第6週 |
3/31 |
General principles of image reading and imaging in cerebrovascular disorders |
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第7週 |
4/7 |
Neuroimaging in acute ischemic stroke |
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第8週 |
4/14 |
Neuroimaging in cerebral hemorrhage, hydrocephalus, traumatic brain injury, and spinal disorders before and after neurosurgery |
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第9週 |
4/21 |
Midterm reports (4 groups) 10-12 mins/group
Identify function-related neural substrates and neural circuits in healthy adults using brain anatomical model/slices, atlas, and images. Functions may include, but is not limited to, sensory, sensory integration, motor, sensori-motor integration, cognition (learning, memory, language, executive function, etc.), emotion, etc. |
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第10週 |
4/28 |
Neuroimaging in white matter lesions, MS, & infection |
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第11週 |
5/5 |
Neuroimaging in brain tumors |
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第12週 |
5/12 |
Neuroimaging in normal aging versus dementia |
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第13週 |
5/19 |
Neuroimaging in Parkinson’s disease and other basal ganglia disorders |
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第14週 |
5/26 |
Pediatric neuroimaging |
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第15週 |
6/2 |
Ultrasonic imaging in adult neurological disorders |
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第16週 |
6/9 |
Neonatal brain ultrasonic imaging |
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第17週 |
6/16 |
Final reports (4 groups; 4 case reports of 4 types of neurological disorders) 10-12 mins/group |
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第18週 |
6/23 |
Final reports (4 groups; 4 case reports of 4 types of neurological disorders) 10-12 mins/group |
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